POLYPHARMACY: MANAGING COMPLEX DRUG INTERACTIONS IN AGING PATIENTS

The increasing number of older adults worldwide has highlighted the importance of safe and effective medication management. Many aging individuals live with multiple chronic conditions and may require several medicines simultaneously. Although appropriate pharmacological treatment can significantly improve disease management and quality of life, the use of multiple medications can also increase the likelihood of drug interactions, adverse reactions, medication-related complications, and challenges in treatment adherence. Polypharmacy: Managing Complex Drug Interactions in Aging Patients provides a comprehensive perspective on the complexities of medication use among older adults. The book explores the causes and consequences of polypharmacy, age-related changes in drug absorption and metabolism, drug–drug and drug–disease interactions, adverse drug events, and approaches for improving medication safety.
Special attention is given to medication assessment, rational prescribing, deprescribing strategies, dose optimization, therapeutic drug monitoring, and collaborative healthcare practices. The importance of individualized medication plans is also emphasized, taking into consideration the patient’s medical conditions, functional abilities, medication history, treatment priorities, and overall health status. This book is designed as a valuable reference for physicians, pharmacists, nurses, geriatric care specialists, researchers, healthcare professionals, academicians, and students. It aims to strengthen understanding of the challenges associated with complex medication regimens and encourage safe, evidence-informed prescribing practices. As modern healthcare increasingly focuses on personalized and patient-centered care, effective management of polypharmacy has become an essential component of geriatric healthcare. This book brings together key concepts and practical approaches to help healthcare professionals minimize medication-related risks, optimize therapeutic outcomes, and promote safer medication use among aging patients.

-Authors